5/5/2025
Last update
5/5/2025
Reviewed By
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 2 Reviews
8.6
Top Medical Research Studies
8
We engaged in a pilot study comparing the effectiveness of polynucleotide sodium with sodium hyaluronate for knee osteoarthritis pain relief. With 15 patients divided into three groups, all received ultrasound-guided injections over three weeks.
Our findings showed that those treated with polynucleotide sodium experienced a significant reduction in weight-bearing pain compared to the hyaluronic acid group after six weeks. However, the other measures of pain and quality of life did not exhibit notable differences between the groups.
Overall, polynucleotide sodium proved more effective in alleviating weight-bearing pain in this limited study.
Our findings showed that those treated with polynucleotide sodium experienced a significant reduction in weight-bearing pain compared to the hyaluronic acid group after six weeks. However, the other measures of pain and quality of life did not exhibit notable differences between the groups.
Overall, polynucleotide sodium proved more effective in alleviating weight-bearing pain in this limited study.
Read More
Most Useful Reviews
9
Significant pain reduction
25 people found this helpful
This really helps reduce my pain. I have bone on bone contact in my knees, but this has considerably lessened my discomfort, allowing me to stand and walk longer without any pain relievers.
Read More
9
Knee pain improved
3 people found this helpful
This product works! My knee pain has improved significantly, and the bone cracking sound when standing has nearly vanished. I take it twice daily and feel much better.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
- All Researches
8
We engaged in a pilot study comparing the effectiveness of polynucleotide sodium with sodium hyaluronate for knee osteoarthritis pain relief. With 15 patients divided into three groups, all received ultrasound-guided injections over three weeks.
Our findings showed that those treated with polynucleotide sodium experienced a significant reduction in weight-bearing pain compared to the hyaluronic acid group after six weeks. However, the other measures of pain and quality of life did not exhibit notable differences between the groups.
Overall, polynucleotide sodium proved more effective in alleviating weight-bearing pain in this limited study.
Our findings showed that those treated with polynucleotide sodium experienced a significant reduction in weight-bearing pain compared to the hyaluronic acid group after six weeks. However, the other measures of pain and quality of life did not exhibit notable differences between the groups.
Overall, polynucleotide sodium proved more effective in alleviating weight-bearing pain in this limited study.
Read More
User Reviews
USERS' SCORE
Good
Based on 2 Reviews
8.6
- All Reviews
- Positive Reviews
- Negative Reviews
9
Significant pain reduction
25 people found this helpful
This really helps reduce my pain. I have bone on bone contact in my knees, but this has considerably lessened my discomfort, allowing me to stand and walk longer without any pain relievers.
Read More
9
Knee pain improved
3 people found this helpful
This product works! My knee pain has improved significantly, and the bone cracking sound when standing has nearly vanished. I take it twice daily and feel much better.
Read More
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- Kim JY, Kim YN, Lee YJ, Sim SE, Ko YR, et al. Pilot Study to Evaluate the Efficacy of Polynucleotide Sodium Compared to Sodium Hyaluronate and Crosslinked Sodium Hyaluronate in Patients with Knee Osteoarthritis. J Clin Med. 2021;10. 10.3390/jcm10051138
